Veterinary Research

What Do Foot-and-Mouth Disease Outbreaks in Europe Mean for the U.S.?

Mon, 31 Mar 2025 13:19:03 GMT

Foot-and-mouth disease (FMD) is rearing its ugly head in Europe. After an outbreak in water buffalo in Germany in January, an outbreak in cattle in Hungary in early March and an outbreak in cattle in Slovakia last week, why now? What is the U.S. doing to keep this foreign animal disease out and protect the country’s livestock industry?

“FMD is caused by a virus that affects cloven-hoofed animals so that can include cattle, pigs, sheep and goats,” explains Megan Niederwerder, DVM, who serves as the executive director of the Swine Health Information Center (SHIC). “It does not affect humans and is not a threat to food safety, but it has significant trade implications once it is introduced into a country.”

FMD has been fairly quiet in these European countries – with no cases reported for decades. Other parts of Europe have seen outbreaks more recently like the 2001 outbreak in the United Kingdom that caused a crisis in British agriculture and tourism and resulted in the cancellation of the World Pork Expo held in Des Moines, Iowa.

“FMD really decimated the United Kingdom,” says Barb Determan who was serving as president of the National Pork Producers Council (NPPC) at the time. “It became very apparent that we couldn’t guarantee the safety for our U.S. pig herd because of the high numbers of international travelers that would be at the show. We had to cancel World Pork Expo out of an abundance of precaution.”

Although there is still a lot to be discovered about how FMD was introduced into these populations, it’s a significant warning to the U.S. to be on alert.

(Lori Hays)

That was the first time, but not the only time World Pork Expo was canceled. The event was also canceled in 2019 because of the African swine fever outbreak in China and again in 2020 due to the COVID-19 pandemic.

“That was a hard financial decision,” Determan says. “We had just completed the separation agreement between NPPC and the National Pork Board. NPPC was very tightly budgeted at that time, so it was a huge hit.”

However, keeping the U.S. pig herd safe was the most important thing on everyone’s mind. She says they made their decision after hearing reports from veterinarians who had been to England to better understand the extensiveness as well as from the USDA that had sent veterinarians over to help.

“At that time, we didn’t have near the biosecurity practices and things that we do now with the disinfectant foot mats,” Determan says. “We also don’t have live pigs on the on the grounds now compared to how we did things many years ago. We used to have live pigs everywhere on the fairgrounds in the early 2000s from genetics companies with pigs in their displays to the pigs in the live shows.”

The Truth About FMD
The clinical signs of FMD are similar to what the name implies. It can cause vesicles or blisters on the feet, mouth and tongue of animals that are infected. The U.S. has not had a case of FMD since 1929.

“We certainly want to keep it that way, as the economic implications for producers are significant if the virus is introduced,” Niederwerder says.

Compared to many viruses, FMD is a highly stable, non-enveloped virus that allows it to be infectious for longer periods. It’s very contagious and highly transmissible. Not only are there risks with transmission of the virus through infected meat products that may come in through illegal trade, but it can also be carried on contaminated clothes or equipment or supplies of humans.

“The human would not be infected, but certainly people can carry the virus on contaminated clothing,” Niederwerder says. “That’s why it’s really important as we think about prevention of entry into the U.S.”

FMD causes fever and pain. It results in excessive salivation and causes reduced milk production in dairy cattle.

“When you think about the impact, certainly there’s an impact on animal health with regards to the clinical signs, but even further is this impact on trade restrictions and the economic losses for producers,” Niederwerder says. “When you try and contain the virus, that oftentimes results in those infected animals being culled or euthanized so the disease no longer has the chance to spread.”

Why Should the U.S. Pay Attention?
When a virus moves into a new geographical range or is reintroduced into a country that has maintained a negative status for a long period, Niederwerder says it’s critical to reassess the risk to the U.S.

“In January, Germany reported their first case in over 30 years in water buffalo near Berlin,” she explains. “It was 14 animals, and those animals were all culled after the infection was confirmed but certainly trade restrictions and implications on surrounding areas of that Berlin farm were significant.”

Fast forward to March when two additional countries have reported cases. Hungary reported FMD in a single farm of cattle in the north part of the country for the first time in over 50 years. Shortly thereafter, the virus appeared in Slovakia (who also hadn’t seen a case in over 50 years) in multiple herds of cattle.

“Just recently, another herd was a suspect herd in Slovakia, near the southern border near Hungary,” Niederwerder says. “This is certainly concerning about how this virus is being reintroduced. Is it associated with contaminated fomites that may be in the country or traveling to new locations? Is it associated with wild boar? Could it be associated with infected hay?”

Although there is still a lot to be discovered about how FMD was introduced into these populations, it’s a significant warning to the U.S. to be on alert .

“We need to do everything we can to make sure it doesn’t get reintroduced into the U.S.,” Niederwerder says. “How can we amp up any biosecurity measures that are necessary to reduce our risk? We also need to think about reducing the risk of introduction into our country through travel and illegal trade.”

Be on Alert
Livestock operations should reevaluate biosecurity protocols. If any of your farm’s employees travel to areas where there are infected animals, implement a quarantine period for entry back into your U.S. farm, she advises.

“Be vigilant,” Niederwerder urges. “One of the challenges of FMD is that it does cause these characteristic lesions of vesicles or blisters on the mouth, nose or the hoof. What becomes very tricky is that those clinical signs are indistinguishable from other vesicular diseases such as Senecavirus A. If producers and veterinarians see these lesions, they must report it immediately so it can be investigated and confirmed that it is not FMD virus.”

FMD is not just a disease of pigs and cattle, she points out. Sheep, goats and cloven-hoofed zoo animals may also be impacted by FMD. This increases the breadth of what the industry needs to monitor.

“The world is very small now,” Niederwerder says. “Not only do people travel more internationally, but animals move around more than ever, too. It’s extremely important for those of us that are producers to keep our eyes open and pay attention to what’s going on worldwide so we can be as prepared as possible for any change in disease risk.”

That’s one of the ways that SHIC is trying to help producers. SHIC provides timely domestic and global disease updates to producers.

“Watching the SHIC global disease report is really important for producers,” Determan says. “It comes out every month and really gives you a feel for what’s happening in the entire world from a swine health standpoint. The biggest lesson we learned from the 2001 FMD outbreak is that looking farther out than just our own farm gate is so important.”

Keep Reading:
An Update on Foot-and-Mouth Disease Virus Serotype O in Germany

Hungary Confirms Foot-and-Mouth Disease Outbreak in Cattle

Slovakia Records First Foot-and-Mouth Cases, Minister Says

10 Understated Things Economists Say Could Impact Agriculture in the New Year

Thu, 26 Dec 2024 16:29:46 GMT

This past year was definitely full of surprises, but there were also happenings in agriculture that economists warned about at the end of 2023.

The bleak outlook for commodity prices, along with elevated interest rates, created a downturn in the ag economy, which is something many economists warned would happen. It’s the speed of which margins crumbled that might have been the bigger surprise.

The latest Ag Economists’ Monthly Monitor asked economists if the U.S. was either in a recession or on the brink of one. The majority of ag economists say U.S. agriculture is ending the year in a recession.

56% of ag economists responded by saying agriculture is currently in a recession, which is up from the 53% who responded that way in October.
81% of economists surveyed said the U.S ag economy is on the brink of a recession, which is a significant jump from the 56% of economists who responded that way in the October survey.

One occurrence that wasn’t on anyone’s radar in 2023: H5N1. What was first thought to be a mystery illness impacting dairy herds in Texas was later confirmed as Highly Pathogenic Avian Flu, the first time the disease was detected in mammals.

At the end of 2024, what are economists watching in 2025? In Farm Journal’s latest Ag Economists’ Monthly Monitor, we asked economists: “What’s the one factor impacting the ag economy that’s not being talked about or covered by the media enough right now?”

From trade to deregulation plus numerous unknowns in a new administration, economists have no shortage of issues they’re watching in the new year.

Here’s What Economists Are Saying:

“The media seems consumed with the negatives of a Trump administration/Republican trifecta. It’s certainly good to be aware of the challenges with any political transition, but more forward thinking on what is positive, would be helpful: the outlook for taxes, biofuels policy, trade deals with agriculture included, deregulation all seem to be potential positives we could be talking about more.”
“Prospective tariff war is being downplayed, despite published research measuring expected range of damage.”
“Farmer attitudes toward alternative land use: CRP, solar and other forms to help diversify incomes.”
“Policy uncertainty is high right now. Will tariffs be imposed and if so, what will be the reaction of other countries? Will the new Administration take regulatory actions that favor or hurt the biofuel industry? What will be the outcome of debates over tax and budgetary policy? Will economic assistance to the farm sector be approved during the lame duck session or in early 2025? What about a new farm bill? Many people are making assumptions about how these questions will be answered, but we don’t know.”
“Farm income varies greatly by region. While we often focus on the Midwest and the financial health of that region, it is also important to notice that regions in the southern U.S. are really struggling.” It is also important to watch what production adjustments producers make to cope with today’s tighter operating margins?
“Could federal budget cuts/austerity dramatically change/reduce the federal farm income safety net?”
“Cash rent prices staying constant during a downturn in crop prices.”
“Let’s be clear — the clean fuels tax credit goes to the fuel producer, not the farmer. It enables market access into the biofuels market for the farm economy, but the ability for the farm economy to capitalize upon it is hamstrung by credit levels that have incentivized large inflows of foreign feedstocks at the expense of literally homegrown feedstocks like SBO.”
“The Brazil real is depreciating, which eventually leads to more U.S. competition.”
“China, Europe, Mexico and others know what to expect out of Trump. They’ve seen it before. Everyone is discounting the possibility that Trump’s tariff threat could result in some pre-emptive trade agreements that benefit us here in the states. The U.S. is the biggest buyer of consumer goods in the world. They can’t afford to cut us off. Note that I said consumer goods, not commodities.”

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Livestock and mRNA Vaccines: What You Need To Know

Fri, 27 Sep 2024 01:56:42 GMT

As misinformation regarding the use of mRNA vaccines in livestock filter through social media, there are facts begging to be set straight.

Recently, a claim was made saying producers are required to inject livestock with mRNA vaccines.

According to USDA spokesperson, Marissa Perry says, “There is no requirement or mandate that producers vaccinate their livestock for any disease. It is a personal and business decision left up to the producer and will remain that way,” in response to the claim, Associated Press shared in an article .

National Pork Board’s Director of Consumer Public Relations, Jason Menke echoed the statement to AP, noting that the decision to use vaccines and other medical treatments to protect animal health and well-being are made by the farmer under the direction of the herd veterinarian.

To further explain mRNA vaccines and shed light on controversies, Dr. Kevin Folta, a molecular biologist and professor at the University of Florida, shares his viewpoint and experience with the technology.

What are mRNA Vaccines?

First introduced to the population through the COVID-19 vaccines, mRNA (messenger ribonucleic acid) vaccines have been in development for decades, says Folta in a recent AgriTalk segment.

He adds that the technology’s potential in human health makes it a likely candidate to have a place in animal health as well. However, “the technology is being maligned in social media, and is now shaping decisions at the level of state legislature,” Folta says. This leads to the growing importance that producers and consumers become more educated on the topic.

What Folta believes began in January of this year, based on claims with very little data, certain advocates against mRNA vaccines are concerned that mRNA vaccines are in use and development in livestock. Additionally, these vaccines may then be present in the food these animals provide.

Why mRNA Vaccines Are Not Present in Food

“It’s not in your food. It’s a vaccine for the animal that, just like any vaccine, protects the animal from disease,” Folta says.

Current mRNA vaccines being used in swine are injected into the muscle, Folta explains, which causes the development of the immune response protein to then stimulate the body to work against the virus.

“In the absence of the virus, it’s kind of like giving the virus or giving the body a ‘wanted’ poster that says, ‘when this individual comes along, and this virus comes along, work against it,’ and it’s all gone within hours,” he adds.

The mRNA never leaves the cells from where it was injected. RNA is a very unstable molecule that must be kept cold, buffered and in solvent, to remain viable, Folta explains.

Additionally, any licensed vaccine comes with a minimum time before that animal can enter the food chain, also known as the “withdrawal time,” says Alan Young, professor in the Department of Veterinary Biomedical Sciences at South Dakota State University and founder of protein platform (non-mRNA) vaccine company Medgene.

The Animal’s Genes Are Not Altered

While mRNA vaccines include genetic code, Folta says the use of a mRNA vaccines does not alter the animal’s genes in any way.

“This [mRNA] is an intermediate between the gene itself and the products that the gene encodes. So, it’s like having a blueprint and a house. The mRNA is like the construction worker. It takes the blueprint and manufactures the house. In the case of the cell, it takes the DNA blueprint and then takes a little bit of that information to build part of the final structure. The mRNA is just that intermediate, it does not change the genes. It doesn’t change the DNA itself,” he explains.

What are the Benefits of mRNA Vaccines?

More flexibility and faster response to new disease, Folta describes as reasons why mRNA vaccines are becoming more popular.

Traditional vaccines require large amounts of a virus to be raised and purified before being injected to elicit an immune response, he adds. Meanwhile, mRNA encourages the body to make a little piece of protein to elicit the desired immune response.

“It’s much cleaner, much easier. If you’re moving parts in this machine, to make this product that induces an immune response, it’s so good in so many ways,” Folta says.

In pork production specifically, researchers are working with mRNA vaccines that will work this way against porcine reproductive and respiratory syndrome (PRRS), which is a viral disease that causes economic loss totals around $664 million per year in the U.S. (Holtkamp et al., 2013).

Additionally, the use of mRNA technology adds another tool to the toolbox, which may be helpful in combating diseases, such as African swine fever (ASF), avian influenza and other food-animal diseases.
“This stands to be a revolutionary technology if we don’t get in the way,” Folta adds.

Are There Risks to mRNA Vaccines?

Folta says everything has some sort of risk, but it’s important to weigh the benefits against the risk.
As seen with the COVID-19 vaccines, in rare cases, people experienced side effects from the vaccine. However, Folta is encouraged by the initial results in livestock.

“If you look in animals where these [vaccines] have been used, there have been no unusual effects noted. Everything potentially has risk, but it’s monitored, and especially in large animal populations, we can look very carefully at that for surveillance,” he explains.

mRNA Enters State Legislation

While some consumers spread misinformation about the use of mRNA vaccines, the ideas have also crept into state legislation.

The Missouri House Bill 1169 , with a special hearing set for Apr. 19 on the matter, aims to require a label be used on meat from animals treated with an mRNA vaccine, identifying the “potential gene therapy product.”
This bill falsely claims that mRNA vaccines would modify the genes of the organism, Folta explains.

mRNA vaccines are simply another modality that can protect animal health, which results in healthy animals producing the best and safest food products, Folta says, and provides producers with more options to help combat disease.

“To have affordable food, we need to have continual innovation in the animal, medical, veterinary space and mRNA vaccines are safe and an effective way to treat the animal that does not change the final product,” he adds.

The COVID-19 pandemic simply “broke the seal” to the development of these new modalities that will change the way human and animal diseases will be treated in the years to come.

More on Vaccines:

Genvax Technologies Secures $6.5 Million to Advance Novel Vaccine Platform

Cattle Veterinarians Have New Vaccination Guidelines

Don’t Assume That Old Refrigerator Is Good Enough To Store Vaccines

OTC Livestock Antibiotics Will Require Prescription June 11